What are
BAT Levels?

What Are BAT Levels?

BAT Levels are biomarkers that measure Beta-Amyloid (Aβ) and Tau (T) in the brain, used to detect early biological drift before symptoms appear.

Summary: BAT Levels measure your brain’s cleanup efficiency by tracking Beta-Amyloid and Tau proteins, offering early insight into biological drift years before symptoms appear.

BAT Levels measure the balance of two key brain proteins, Beta-Amyloid (Aβ) and Tau (T), that form the foundation of brain cleanup and repair. When these proteins build up faster than your brain can clear them, it signals an early imbalance known as biological drift.

Unlike cognitive or imaging tests that only detect damage after it occurs, BAT Levels provide a real-time biological snapshot of your brain’s cleanup performance, allowing action years before symptoms start.

Understanding the Biology Behind BAT Levels

Every brain produces Beta-Amyloid and Tau as part of normal metabolism. Under healthy conditions, these proteins are cleared through glymphatic flow and cellular autophagy. But when that system slows—due to age, inflammation, poor sleep, or genetics—they begin to accumulate.

Over time, this buildup forms the biological groundwork for neurodegeneration. Monitoring BAT Levels gives clinicians and individuals an objective way to track how efficiently the brain is maintaining its internal hygiene.

Key points:

• Beta-Amyloid (Aβ): Fragments of protein that, when un-cleared, form plaques that disrupt neural communication.
• Tau (T): Structural protein that, when hyperphosphorylated, forms tangles inside neurons.
• BAT Levels: The relative balance and accumulation rate of these two markers, expressed as a biological risk ratio.

This ratio changes long before symptoms appear, making it the earliest measurable sign of drift in brain health.

Why BAT Levels Are Considered the #1 Biomarker for Brain Health

BAT Levels are powerful because they merge decades of biomarker research with next-generation lab testing and AI-driven interpretation.

Traditional brain scans or memory tests detect decline only after damage occurs. BAT Levels instead reflect the biological mechanisms that lead to that decline, giving time to intervene before it becomes irreversible.

Core advantages:

• Detects drift up to 20 years before symptoms
• Provides a clear, numeric score for tracking over time
• Integrates with metabolic and genetic data for precision prevention
• Enables clinicians to tailor interventions based on biological rather than behavioral signs

Because of these traits, BAT Levels have become the cornerstone of proactive brain health monitoring worldwide.

What BAT Levels Reveal About Brain Aging

Biological drift doesn’t happen overnight. It starts quietly, often in a person’s 30s or 40s, as microglial activity and cerebrospinal clearance slow.

BAT Levels act like your brain’s “check-engine light.” They show when your cleanup system is lagging and by how much, offering a measurable path back to stability.

Typical trajectory:

• Optimal (Optimal Range): Low Aβ/T ratio, balanced metabolism
• Early Drift (Watch Range): Slight accumulation, reversible with short-term intervention
• Elevated (Action Range): Ongoing buildup, requires medical management and follow-up BATReset cycle

How BAT Levels Are Measured

BAT Levels are determined through a proprietary, multi-step lab process called BAT Testing, which analyzes blood for Beta-Amyloid and Tau biomarkers.

Steps include:

• Sample Collection: Simple blood draw, no spinal tap or imaging required
• Biomarker Quantification: Measurement of Aβ and Tau concentrations
• Ratio & Drift Scoring: AI-assisted algorithms calculate the BATScore
• Clinical Interpretation: A certified BATWatch clinician reviews your data

This standardized approach yields ~99.5% analytical accuracy when performed within the BAT Labs network.

Factors That Influence BAT Levels

Several variables affect how BAT Levels change over time:

Understanding these drivers allows targeted interventions to slow, stop, or reverse drift.

Managing and Reducing BAT Levels

Once BAT Levels are identified as elevated, a BATReset cycle can help normalize them. This includes:

• A short-term course of BAT Pill (Sirolimus) to modulate mTOR and enhance autophagy
• Nutritional optimization (omega-3s, antioxidants)
• Lifestyle recalibration (sleep, exercise, stress reduction)
• Annual BATCheck monitoring to confirm sustained balance

This cyclical model parallels cholesterol management—measure, reset, recheck—but applies it to the brain.

Insurance, Access, and Safety

BAT Testing and BAT Level management are available through the BATWatch clinical network and often covered by major insurance providers.

All BAT Labs operate under CLIA certification, and testing follows validated laboratory-developed test (LDT) standards.

Out-of-network patients may self-pay, and all participants receive full transparency on lab and review fees.

Summary

BAT Levels give your brain a measurable metric of biological performance, a way to detect drift early, act precisely, and stay ahead of decline.

This is proactive medicine: catching what’s changing while there’s still time to change it.

Note: BAT Levels refer to brain biomarkers, not brown adipose tissue or other unrelated meanings of “BAT.”

Reference:

BATWatch Research Group (2025). BAT Testing and BATCheck: Translating Biomarkers Into Preventive Insight. Zenodo. https://doi.org/

© 2025 BATWatch Research Group (TeamBrain, Inc., USA). Distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0).  Non-commercial citation permitted with attribution. 

Trademark Notice: BATophagy, BATWatch, BATReset, BATCheck, BATLevels, BATPill, BATTest, and BATScore are proprietary concepts of TeamBrain, Inc. Other BAT-related terminology used within this publication forms part of the TeamBrain intellectual framework and is used here for scientific and descriptive purposes only.